The brand had recently released a series of ad campaigns encouraging female football fans to "Get Your Game Face On" with looks inspired by 32 NFL teams.
One photo in particular features a model sporting the colours and drawn on wings of the Baltimore Ravens.
Protesters posted the photoshopped image of the model with a black eye to Twitter and Facebook while
calling for the resignation of the NFL's commissioner Roger Goodell and a boycott of the league following player Ray Rice's altercation with his now wife, in Atlantic City elevator.
Rice was only cut by the Baltimore Ravens and suspended indefinitely from the NFL after a video surfaced last week of him punching his then-fiancee.
The league is being criticized for how it handled the case because Rice was originally suspended for just two games. Goodell has since admitted that was a mistake.
Since then, the NFL has established a six-game unpaid ban for those who violate its policy on domestic violence.
CoverGirl ways in..
After the photoshopped image went viral, CoverGirl released a statement saying it supports women, stands for female empowerment and believes domestic violence is completely unacceptable.
"We developed our NFL program to celebrate the more than 80 million female football fans. In light of recent events, we have encouraged the NFL to take swift action on their path forward to address the issue of domestic violence," said reps.
Rice has since appealed the indefinite suspension from the NFL but the outcry for a long, hard look at the league's history of forgiveness for domestic violence has only continued to get louder over the past seven days.