NOT ALL BIOACTIVES ARE CREATED EQUAL. Maplifa® is a proprietary, patent-pending red maple (Acer rubrum) leaf extract standardized to polyphenols and glucitol-core containing gallotannins (GCGs). GCGs have been reported to show inhibitory effects on the formation of advanced glycation endproducts (AGEs) which are key biomarkers known to contribute to aging-related skin conditions, such as sagging and wrinkles.